Role of Epidermal and Fibroblast Growth Factors in Pancreatic Development
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Combined Effect of Retinoic Acid and Basic Fibroblast Growth Factor on Maturation of Mouse Oocyte and Subsequent Fertilization and Development
Objective Many autocrine and paracrine elements that are produced within follicular niche have been the focus of much in vitro maturation research. The present study was carried out to compare retinoic acid and basic fibroblast growth factor (bFGF) efficacy on IVM of mouse oocytes, and their further dual consumption to reach an optimal protocol. MaterialsAndMethods GV oocytes obtained from two-...
متن کاملDevelopment of an Allogeneic Cultured Dermal Substitute Using a Standard Human Fibroblast Bank
Background: Fibroblasts are mesenchymal cells that can be readily cultured in the laboratory and play a significant role in epithelialmesenchymal interactions, secreting various growth factors and cytokines that have a direct effect on epidermal proliferation, differentiation and formation of extracellular matrix. They have been incorporated into various tissue-engineered and used for a variety...
متن کاملP-128: Fibroblast Growth Factor Improves Oocyte Maturation in Vitrified-Thawed Mouse Follicles
Background: The fibroblast growth factors (FGF-4) are a group of heparin-binding single chain polypeptides that play a pivotal role in development, cell growth, tissue repairing and transformation. The aim of this study is to improve development and maturation outcome of vitrified mouse pre-antral follicle by adding of fibroblast growth factor (FGF) into medium culture. Materials and Methods: P...
متن کاملPancreatic cancer: the role of pancreatic stellate cells in tumor progression.
Pancreatic ductal adenocarcinoma is an aggressive and highly lethal disease frequently characterized by a dense stromal or desmoplastic response. Accumulating evidence exists that tumor desmoplasia plays a central role in disease progression and that e.g. activated pancreatic stellate cells (PSCs) are responsible for the excess matrix production. The mechanisms underlying the tumor versus strom...
متن کاملP-107: Vitrification and In Vitro Culture of Mouse Preantral Follicles in Presence of Growth Factors
Background: Cryopreservation of oocytes is an effective technology in assisted reproductive technology. Although successful vitrification of gametes has been reported in several mammalian species, the survival is generally low. The aim of this study was to investigate the effects of fibroblast growth factor (FGF) and hepatocyte growth factor (HGF) on preantral follicle development after vitrifi...
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تاریخ انتشار 2003